Granisetron Baxter 1 mg/ml solution for injection 10 × 1ml , Baxter Deutschland GmbH
Indication
The active ingredient contained in the medicine is granisetron. It belongs to a group of medicines called “5-HT3 receptor antagonists” or “antiemetics”.
The medicine is used to prevent or treat nausea and vomiting caused by other medical treatments, including chemotherapy or radiation therapy for cancer or after surgery.
The medicine is indicated for adults and children aged 2 years and over.
Contraindication
The medicine must not be used
if you are hypersensitive (allergic) to granisetron or any of the other ingredients of the medicine.
If you are unsure, talk to your doctor, pharmacist or nurse before having the injection.
Dosage
The injection will be given to you by a doctor or nurse. The dose of the medicine varies from patient to patient. It depends on your age, weight and whether you are receiving the medicine to prevent or treat nausea and vomiting. Your doctor will determine which dose is right for you.
Prevention of nausea or vomiting after radiation or chemotherapy
The injection will be given to you before your radiotherapy or chemotherapy starts. The injection into one of your veins takes between 30 seconds and 5 minutes and the usual dose is between 1 and 3 mg. The medicine may be diluted before injection.
Treatment of nausea or vomiting after radiation or chemotherapy
The injection takes between 30 seconds and 5 minutes and the usual dose is between 1 and 3 mg. The medicine may be diluted before being injected into your vein. After the first dose, you may be given further injections to control your symptoms. These injections are given at least 10 minutes apart. You will be given a maximum of 9 mg of granisetron per day.
Combination with steroids
The effectiveness of the injection can be improved by using certain medicines called adrenocorticosteroids. As a steroid, you will be given either a dose of 8 to 20 mg of dexamethasone before radiotherapy or chemotherapy, or 250 mg of methylprednisolone, given both before and after radiotherapy or chemotherapy.
Use in children to prevent or treat nausea or vomiting after radiation or chemotherapy
In children, the medicine is given as an injection into a vein as described above, with the dose depending on the child’s weight. The injections are diluted and given over a period of 5 minutes before the start of radiotherapy or chemotherapy. Children receive a maximum of 2 doses per day, at least 10 minutes apart.
Treating nausea or vomiting after surgery
The injection into your vein takes between 30 seconds and 5 minutes and the usual dose is 1 mg. The maximum dose of granisetron administered is 3 mg per day.
Use in children to prevent or treat nausea or vomiting after surgery
Children should not receive this injection to treat nausea or vomiting after surgery.
If you have used more than you should
Because the medicine will be given to you by a doctor or nurse, it is unlikely that you will be given too much. However, if you have any concerns, speak to your doctor or nurse. Symptoms of an overdose include a mild headache. You will be treated symptomatically.
If you have any further questions about using the medicine, talk to your doctor, pharmacist or nurse.
