Key points of the drug for osteoporosis Fosamax:
Fosamax is often prescribed to patients with osteoporosis, advanced cancer, and Paget’s disease to prevent bone loss (which is a common symptom of these diseases).
More than 10 million people are taking or have taken fosamax, the most effective bisphosphonate drug.
Fosamax is usually taken as a tablet on an empty stomach.
Most patients are prescribed Fosamax to treat the symptoms of osteoporosis, which is characterized by thinning of the bones, a condition that is especially common in postmenopausal women.
Please note that the use of food, coffee or orange juice along with Fosamax reduces the bioavailability of the drug by 60%.
Information for professionals:
The trade name of the product is Fosamax®
International non-proprietary name INN – alendronic acid
Systematic name sodium trihydroxide-(4-amino-1-hydroxybutylidene)diphosphonate trihydrate
Pharmacotherapeutic group – Bisphosphonate, an inhibitor of bone resorption.
Dosage form – tablets
Medicines containing alendronic acid as an active ingredient, as well as fosamax bisphosphonate, are dispensed in Czech pharmacies by prescription.
What is Fosamax used for?
The package insert for this product lists the following indications for use:
treatment of osteoporosis in postmenopausal women (fracture prevention)
prevention of osteoporosis with the risk of its development in women during menopause (reducing the likelihood of fractures)
treatment of osteoporosis in men (prevention of fractures);
treatment of glucocorticoid-induced osteoporosis
Paget’s disease of the bone
Keep in mind. What you should not take Fosamax. If you are allergic to alendronate, or if you have low blood calcium levels (hypocalcemia) or problems (difficulty) passing food down the esophagus.
Fosamax bisphosphonate can cause serious stomach or esophageal problems. You must remain upright for at least 30 minutes after taking the medicine.
To make sure Fosamax is right for you, tell your doctor if you have:
Difficulty swallowing
Vitamin D deficiency
dental problems
kidney disease
stomach disease
Dosage and method of application of the drug Fosamax
Fosamax is intended for oral administration. It is taken at least half an hour before meals in the morning, immediately after waking up. Swallow the tablet with clean water. Any other drinks reduce the absorption of the drug.
In order to avoid irritation of the esophagus when taking Fosamax, it is recommended to follow the following instructions: take the tablet in the morning immediately after getting out of bed; swallow the tablet with a full glass of clean water, without chewing or dissolving the tablet in the mouth; it is not recommended to lie down before the first meal (at least 30 minutes after taking the pill). Do not take Fosamax before getting out of bed or at bedtime.
In case of insufficient intake of vitamin D and calcium, the simultaneous use of appropriate drugs is recommended.
The therapeutic dose of Fosamax in the treatment of osteoporosis is 70 mg (1 tablet once a week.
The dosage for the prevention of osteoporosis is 5 mg per day.
The dose in the treatment of glucocorticoid-induced osteoporosis is 5 mg per day.
The dose in the treatment of Paget’s disease is 40 mg per day for 6 months.
Side effects
During clinical trials, side effects were rare, and their frequency was less than 1%. However, among them, the following side reactions are most often observed:
Constipation
Flatulence
Muscle pain
Pain in the bones
Headache
Dyspepsia
Diarrhea
Nausea
Abdominal pain
In rare cases, this osteoporosis medicine can cause bone loss in the jaws. Symptoms of this condition include: jaw pain or numbness, redness or swelling of the gums, loose teeth, or slow healing after dental procedures. The longer the patient takes Fosamax, the greater the likelihood of developing this disease.
Who is contraindicated in the drug for osteoporosis Fosamax?
You must be familiar with all contraindications. The main contraindications include:
Diseases of the esophagus, especially achalasia and esophageal stricture
Inability to stand upright for 30 minutes or more.
Decreased calcium levels in the bloodstream.
Hypersensitivity to any component of the drug Fosamax.
Pregnancy and lactation
Very carefully, alendronic acid for the treatment of bone thinning is prescribed for exacerbation of any disease of the stomach or intestines, especially with dysphagia, gastritis, duodenitis or stomach ulcers. In addition, dose adjustment is required if creatinine clearance is below 35 ml/min.
Drug Interactions
The absorption of alendronic acid may be affected by the use of antacids, calcium-containing drugs, and other oral medications. The interval between taking Fosamax and other drugs should be more than 30 minutes. With the simultaneous use of glucocorticoids, there is no significant interaction with drugs.
If you miss the next dose of Fosamax (according to the scheme 1 tablet per week), it is recommended to take the next dose the next morning. After that, it is recommended to return to the selected regimen of the drug. Do not take 2 tablets on the same day.
Although Fosamax is available in some pharmacies without a prescription, this drug should be used under the supervision of a physician.
Buy Fosamax
Price Fosamax
Цена Fosamax
Купить Fosamax
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Precio Fosamax
Key points of the drug for osteoporosis Fosamax:
Fosamax is often prescribed to patients with osteoporosis, advanced cancer, and Paget’s disease to prevent bone loss (which is a common symptom of these diseases).
More than 10 million people are taking or have taken fosamax, the most effective bisphosphonate drug.
Fosamax is usually taken as a tablet on an empty stomach.
Most patients are prescribed Fosamax to treat the symptoms of osteoporosis, which is characterized by thinning of the bones, a condition that is especially common in postmenopausal women.
Please note that the use of food, coffee or orange juice along with Fosamax reduces the bioavailability of the drug by 60%.
Information for professionals:
The trade name of the product is Fosamax®
International non-proprietary name INN – alendronic acid
Systematic name sodium trihydroxide-(4-amino-1-hydroxybutylidene)diphosphonate trihydrate
Pharmacotherapeutic group – Bisphosphonate, an inhibitor of bone resorption.
Dosage form – tablets
Medicines containing alendronic acid as an active ingredient, as well as fosamax bisphosphonate, are dispensed in Czech pharmacies by prescription.
What is Fosamax used for?
The package insert for this product lists the following indications for use:
treatment of osteoporosis in postmenopausal women (fracture prevention)
prevention of osteoporosis with the risk of its development in women during menopause (reducing the likelihood of fractures)
treatment of osteoporosis in men (prevention of fractures);
treatment of glucocorticoid-induced osteoporosis
Paget’s disease of the bone
Keep in mind. What you should not take Fosamax. If you are allergic to alendronate, or if you have low blood calcium levels (hypocalcemia) or problems (difficulty) passing food down the esophagus.
Fosamax bisphosphonate can cause serious stomach or esophageal problems. You must remain upright for at least 30 minutes after taking the medicine.
To make sure Fosamax is right for you, tell your doctor if you have:
Difficulty swallowing
Vitamin D deficiency
dental problems
kidney disease
stomach disease
Dosage and method of application of the drug Fosamax
Fosamax is intended for oral administration. It is taken at least half an hour before meals in the morning, immediately after waking up. Swallow the tablet with clean water. Any other drinks reduce the absorption of the drug.
In order to avoid irritation of the esophagus when taking Fosamax, it is recommended to follow the following instructions: take the tablet in the morning immediately after getting out of bed; swallow the tablet with a full glass of clean water, without chewing or dissolving the tablet in the mouth; it is not recommended to lie down before the first meal (at least 30 minutes after taking the pill). Do not take Fosamax before getting out of bed or at bedtime.
In case of insufficient intake of vitamin D and calcium, the simultaneous use of appropriate drugs is recommended.
The therapeutic dose of Fosamax in the treatment of osteoporosis is 70 mg (1 tablet once a week.
The dosage for the prevention of osteoporosis is 5 mg per day.
The dose in the treatment of glucocorticoid-induced osteoporosis is 5 mg per day.
The dose in the treatment of Paget’s disease is 40 mg per day for 6 months.
Side effects
During clinical trials, side effects were rare, and their frequency was less than 1%. However, among them, the following side reactions are most often observed:
Constipation
Flatulence
Muscle pain
Pain in the bones
Headache
Dyspepsia
Diarrhea
Nausea
Abdominal pain
In rare cases, this osteoporosis medicine can cause bone loss in the jaws. Symptoms of this condition include: jaw pain or numbness, redness or swelling of the gums, loose teeth, or slow healing after dental procedures. The longer the patient takes Fosamax, the greater the likelihood of developing this disease.
Who is contraindicated in the drug for osteoporosis Fosamax?
You must be familiar with all contraindications. The main contraindications include:
Diseases of the esophagus, especially achalasia and esophageal stricture
Inability to stand upright for 30 minutes or more.
Decreased calcium levels in the bloodstream.
Hypersensitivity to any component of the drug Fosamax.
Pregnancy and lactation
Very carefully, alendronic acid for the treatment of bone thinning is prescribed for exacerbation of any disease of the stomach or intestines, especially with dysphagia, gastritis, duodenitis or stomach ulcers. In addition, dose adjustment is required if creatinine clearance is below 35 ml/min.
Drug Interactions
The absorption of alendronic acid may be affected by the use of antacids, calcium-containing drugs, and other oral medications. The interval between taking Fosamax and other drugs should be more than 30 minutes. With the simultaneous use of glucocorticoids, there is no significant interaction with drugs.
If you miss the next dose of Fosamax (according to the scheme 1 tablet per week), it is recommended to take the next dose the next morning. After that, it is recommended to return to the selected regimen of the drug. Do not take 2 tablets on the same day.
Although Fosamax is available in some pharmacies without a prescription, this drug should be used under the supervision of a physician.
Buy Fosamax
Price Fosamax
Цена Fosamax
Купить Fosamax
Acheter Fosamax
Prix Fosamax
Comprar Fosamax
Precio Fosamax
